Shiozaki M, Tashiro T, Koshino H, Nakagawa R, Inoue S, Shigeura T, Watarai H, Taniguchi M, Mori K.
Synthesis and biological activity of ester and ether analogues of α-galactosylceramide (KRN7000). Carbohydr Res 345(12):1663-1684 (2010).
Watarai H, Fujii SI, Yamada D, Rybouchkin A, Sakata S, Nagata Y, Iida-Kobayashi M, Sekine-Kondo E, Shimizu K, Shozaki Y, Sharif J, Matsuda M, Mochiduki S, Hasegawa T, Kitahara G, Endo T, Toyoda T, Ohara O, Harigaya KI, Koseki H, Taniguchi M.
Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells. J Clin Invest 120(7):2610–2618 (2010).
Tashiro T, Sekine-Kondo E, Shigeura T, Nakagawa R, Inoue S, Omori-Miyake M, Chiba T, Hongo N, Fujii SI, Shimizu K, Mori K, Yoshiga Y, Sumida T, Watarai H, Taniguchi M.
Induction of Th1-biased cytokine production by α-carba-GalCer, a neoglycolipid ligand for natural killer T cells. Int Immunol 22(4):319-328 (2010).
Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C.
Regulation of IL-9 expression by IL-25 signaling. Nat Immunol 11(3):250-256 (2010).
Matsuoka N, Itoh T, Watarai H, Sekine-Kondo E, Nagata N, Okamoto K, Mera T, Yamamoto H, Yamada S, Maruyama I, Taniguchi M, Yasunami Y.
High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice. J Clin Invest 120(3):735–743 (2010).
Watarai H, Rybouchkin A, Hongo N, Nagata Y, Sakata S, Sekine E, Dashtsoodol N, Tashiro T, Fujii SI, Shimizu K, Mori K, Masuda K, Kawamoto H, Koseki H, Taniguchi M.
Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant Vα14-Jα18 TCRα gene. Blood 115(2):230-237 (2010).
Taniguchi M, Tashiro T, Dashtsoodol N, Hongo N, Watarai H.
The specialized iNKT cell system recognizes glycolipid antigens and bridges the innate and acquired immune systems with potential applications for cancer therapy. Int Immunol 22(1):1-6 (2010).
Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, Ito M, Watarai H, Hazelett CC, Yeaman C, Ohno H.
M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex. Nat Cell Biol 11(12):1427-1432 (2009).
Tashiro T, Nakagawa R, Hirokawa T, Inoue S, Watarai H, Taniguchi M, Mori K.
RCAI-37, 56, 59, 60, 92, 101, and 102, cyclitol and carbasugar analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines. Bioorg Med Chem 17(17):6360-6373 (2009).
Terashima A, Watarai H, Inoue S, Sekine E, Nakagawa R, Hase K, Iwamura C, Nakajima H, Nakayama T, Taniguchi M.
A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. J Exp Med 205(12):2727-2733 (2008).
Dashtsoodol N, Watarai H, Sakata S, Taniguchi M.
Identification of CD4-CD8- double-negative natural killer T cell precursors in the thymus. PLoS One 3(11):e3688 (2008).
Tashiro T, Hongo N, Nakagawa R, Seino KI, Watarai H, Ishii Y, Taniguchi M, Mori K.
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines. Bioorg Med Chem 16(19):8896-8906 (2008).
Nishikawa T, Takayama A, Watarai H, Taniguchi M, Hori S.
Domain requirements of the FoxP3 transcription factor for the development and function of regulatory T-cells. Immunology 125:121 (2008).
Hossain MB, Hosokawa H, Hasegawa A, Watarai H, Taniguchi M, Yamashita M, Nakayama T.
Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells. Immunology 125(3):377-386 (2008).
Tashiro T, Nakagawa R, Inoue S, Shiozaki M, Watarai H, Taniguchi M, Mori K.
RCAI-61, the 6'-methylated analog of KRN7000: its synthesis and potent activity for mouse lymphocytes to produce interferon-γ in vivo. Tetrahedron Lett 49(48):6827-6830 (2008).
Watarai H, Sekine E, Inoue S, Nakagawa R, Kaisho T, Taniguchi M.
PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon. Proc Natl Acad Sci USA 105(8):2993-2998 (2008).
Watarai H, Nakagawa R, Omori-Miyake M, Dashtsoodol N, Taniguchi M.
Methods for detection, isolation and culture of mouse and human invariant NKT cells. Nat Protoc 3(1):70-78 (2008).
Shinohara H, Maeda S, Watarai H, Kurosaki T.
IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells. J Exp Med 204(13):3285-3293 (2007).
Hijikata A, Kitamura H, Kimura Y, Yokoyama R, Aiba Y, Bao Y, Fujita S, Hase K, Hori S, Ishii Y, Kanagawa O, Kawamoto H, Kawano K, Koseki H, Kubo M, Kurita-Miki A, Kurosaki T, Masuda K, Nakata M, Oboki K, Ohno H, Okamoto M, Okayama Y, O-Wang J, Saito H, Saito T, Sakuma M, Sato K, Sato K, Seino K, Setoguchi R, Tamura Y, Tanaka M, Taniguchi M, Taniuchi I, Teng A, Watanabe T, Watarai H, Yamasaki S, Ohara O.
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics 23(21):2934-2941 (2007).
Tashiro T, Nakagawa R, Hirokawa T, Inoue S, Watarai H, Taniguchi M, Mori K.
RCAI-56, a carbocyclic analogue of KRN7000: its synthesis and potent activity for natural killer (NK)T cell to preferentially produce interferon-γ. Tetrahedron Lett 48(19):3343-3347 (2007).
Dashtsoodol N, Iwabuchi K, Hedlund E, Murakawa S, Shirai K, Iwabuchi C, Kon Y, Miyazaki Y, Yanagawa Y, Onoe K.
Characterization of NKT-cell hybridomas expressing invariant T-cell antigen receptors. J Clin Exp Hematol 47:1-8 (2007).
Harada M, Magara-Koyanagi K, Watarai H, Nagata Y, Ishii Y, Kojo S, Horiguchi S, Okamoto Y, Nakayama T, Suzuki N, Yeh WC, Akira S, Kitamura H, Ohara O, Seino K, Taniguchi M.
IL-21-induced Bε cell apoptosis mediated by natural killer T cells suppresses IgE responses. J Exp Med 203(13):2929-2937 (2006).
Baba Y, Hayashi K, Fujii Y, Mizushima A, Watarai H, Wakamori M, Numaga T, Mori Y, Iino M, Hikida M, Kurosaki T.
Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum. Proc Natl Acad Sci USA 103(45):16704-16709 (2006).
Jiang X, Morita M, Sugioka A, Harada M, Kojo S, Wakao H, Watarai H, Ohkohchi N, Taniguchi M, Seino K.
The importance of CD25+ CD4+ regulatory T cells in mouse hepatic allograft tolerance. Liver Transplant 12(7):1112-1118 (2006).
Dashtsoodol N.
The differentiation pathway of NKT cells in the thymus. Hokkaido J Med Sci 81(6):505-514 (2006).
Shinohara H, Yasuda T, Aiba Y, Sanjo H, Hamadate M, Watarai H, Sakurai H, Kurosaki T.
PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1. J Exp Med 202(10):1423-1431 (2005).
Watarai H, Hinohara A, Nagafune J, Nakayama T, Taniguchi M, Yamaguchi Y.
Plasma membrane-focused proteomics: dramatic changes in surface expression during the maturation of human dendritic cells. Proteomics 5(15):4001-4011 (2005).
Kojo S, Seino K, Harada M, Watarai H, Wakao H, Uchida T, Nakayama T, Taniguchi M.
Induction of regulatory properties in dendritic cells by Vα14 NKT cells. J Immunol 175(6):3648-5365 (2005).
Jiang X, Shimaoka T, Kojo S, Harada M, Watarai H, Wakao H, Ohkohchi N, Yonehara S, Taniguchi M, Seino K.
Cutting edge: critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance. J Immunol 175(4):2051-2055 (2005).
Kimura MY, Hosokawa H, Yamashita M, Hasegawa A, Iwamura C, Watarai H, Taniguchi M, Takagi T, Ishii S, Nakayama T.
Regulation of T helper type 2 cell differentiation by murine Schnurri-2. J Exp Med 201(3):397-408 (2005).
Feese MD, Tamada T, Kato Y, Maeda Y, Hirose M, Matsukura Y, Shigematsu H, Muto T, Matsumoto A, Watarai H, Ogami K, Tahara T, Kato T, Miyazaki H, Kuroki R.
Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment. Proc Natl Acad Sci USA 101(7):1816-1821 (2004).
Nakai Y, Iwabuchi K, Fujii S, Ishimori N, Dashtsoodol N, Watano K, Mishima T, Iwabuchi C, Tanaka S, Bezbradica JS, Nakayama T, Taniguchi M, Miyake S, Yamamura T, Kitabatake A, Joyce S, Van Kaer L, Onoe K.
Natural killer T cells accelerate atherogenesis in mice. Blood 104:2051-2059 (2004).
Kuroki R, Hirose M, Kato Y, Feese MD, Tamada T, Shigematsu H, Watarai H, Maeda Y, Tahara T, Kato T, Miyazaki H.
Crystallization of the functional domain of human thrombopoietin using an antigen-binding fragment derived from neutralizing monoclonal antibody. Acta Crystallogr 58(Pt 5):856-858 (2002).